V014-5649 Screening compound: 1-[6-(2,4-difluorobenzoyl)-4-(4-methylphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]pyrrolidine

V014-5649 Screening compound: 1-[6-(2,4-difluorobenzoyl)-4-(4-methylphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]pyrrolidine
V014-5649 Screening compound: 1-[6-(2,4-difluorobenzoyl)-4-(4-methylphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]pyrrolidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-5649
1-[6-(2,4-difluorobenzoyl)-4-(4-methylphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]pyrrolidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-5649

Molecular Formula

C25H24F2N4O2 (C25 H24 F2 N4 O2)

Compound Name

1-[6-(2,4-difluorobenzoyl)-4-(4-methylphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]pyrrolidine

IUPAC name

1-[6-(24-difluorobenzoyl)-4-(4-methylphenoxy)-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]pyrrolidine

SMILES

Cc(cc1)ccc1Oc1c(CN(CC2)C(c(ccc(F)c3)c3F)=O)c2nc(N2CCCC2)n1

InChI

InChI=1S/C25H24F2N4O2/c1-16-4-7-18(8-5-16)33-23-20-15-31(24(32)19-9-6-17(26)14-21(19)27)13-10-22(20)28-25(29-23)30-11-2-3-12-30/h4-9,14H,2-3,10-13,15H2,1H3

InChI Key

ZFDQMSWREQVLPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19908176

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

450.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.483

Distribution Coefficient, logD

5.483

Water Solubility, LogSw

-5.37

Polar Surface Area

46.871

Acid Dissociation Constant (pKa)

19.71

Base Dissociation Constant (pKb)

1.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

References: we are preparing a list of scientific research reports with V014-5649 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-5649?
Check Price and Availability of V014-5649, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-5649 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-5649
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-5649
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-5649 available by request