V014-6375 Screening compound: 3-(2-chlorophenyl)-3-(7-ethyl-1H-indol-3-yl)-N-propylpropanamide

V014-6375 Screening compound: 3-(2-chlorophenyl)-3-(7-ethyl-1H-indol-3-yl)-N-propylpropanamide
V014-6375 Screening compound: 3-(2-chlorophenyl)-3-(7-ethyl-1H-indol-3-yl)-N-propylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-6375
3-(2-chlorophenyl)-3-(7-ethyl-1H-indol-3-yl)-N-propylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-6375

Molecular Formula

C22H25ClN2O (C22 H25 ClN2 O)

Compound Name

3-(2-chlorophenyl)-3-(7-ethyl-1H-indol-3-yl)-N-propylpropanamide

IUPAC name

3-(2-chlorophenyl)-3-(7-ethyl-1H-indol-3-yl)-N-propylpropanamide

SMILES

CCCNC(CC(c1c[nH]c2c1cccc2CC)c(cccc1)c1Cl)=O

InChI

InChI=1S/C22H25ClN2O/c1-3-12-24-21(26)13-18(16-9-5-6-11-20(16)23)19-14-25-22-15(4-2)8-7-10-17(19)22/h5-11,14,18,25H,3-4,12-13H2,1-2H3,(H,24,26)/t18-/m1/s1

InChI Key

MMFBMTYNQLWSHO-GOSISDBHSA-N

MDL Number (MFCD)

MFCD19853537

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.91

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.249

Distribution Coefficient, logD

5.249

Water Solubility, LogSw

-5.72

Polar Surface Area

34.921

Acid Dissociation Constant (pKa)

14.51

Base Dissociation Constant (pKb)

-0.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

V014-6375 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Glucocorticoid receptors Library (4806 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V014-6375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-6375?
Check Price and Availability of V014-6375, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-6375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-6375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-6375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-6375 available by request