V014-6691 Screening compound: N~1~-{2-[(2-benzyl-7-chloro-4-quinazolinyl)amino]ethyl}-3-fluorobenzamide

V014-6691 Screening compound: N~1~-{2-[(2-benzyl-7-chloro-4-quinazolinyl)amino]ethyl}-3-fluorobenzamide
V014-6691 Screening compound: N~1~-{2-[(2-benzyl-7-chloro-4-quinazolinyl)amino]ethyl}-3-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-6691
N~1~-{2-[(2-benzyl-7-chloro-4-quinazolinyl)amino]ethyl}-3-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-6691

Molecular Formula

C24H20ClFN4O (C24 H20 ClFN4 O)

Compound Name

N~1~-{2-[(2-benzyl-7-chloro-4-quinazolinyl)amino]ethyl}-3-fluorobenzamide

IUPAC name

n/a

SMILES

O=C(c1cc(F)ccc1)NCCNc1c(ccc(Cl)c2)c2nc(Cc2ccccc2)n1

InChI

InChI=1S/C24H20ClFN4O/c25-18-9-10-20-21(15-18)29-22(13-16-5-2-1-3-6-16)30-23(20)27-11-12-28-24(31)17-7-4-8-19(26)14-17/h1-10,14-15H,11-13H2,(H,28,31)(H,27,29,30)

InChI Key

PNUZZLVOWSJLOH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19780739

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.340

Distribution Coefficient, logD

5.248

Water Solubility, LogSw

-6.07

Polar Surface Area

54.486

Acid Dissociation Constant (pKa)

12.57

Base Dissociation Constant (pKb)

6.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

V014-6691 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V014-6691 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-6691?
Check Price and Availability of V014-6691, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-6691 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-6691
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-6691
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-6691 available by request