V014-8437 Screening compound: 4,5-dimethyl-2-(4-methylphenyl)-6-[4-(naphthalene-2-sulfonyl)piperazin-1-yl]pyrimidine

V014-8437 Screening compound: 4,5-dimethyl-2-(4-methylphenyl)-6-[4-(naphthalene-2-sulfonyl)piperazin-1-yl]pyrimidine
V014-8437 Screening compound: 4,5-dimethyl-2-(4-methylphenyl)-6-[4-(naphthalene-2-sulfonyl)piperazin-1-yl]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-8437
4,5-dimethyl-2-(4-methylphenyl)-6-[4-(naphthalene-2-sulfonyl)piperazin-1-yl]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-8437

Molecular Formula

C27H28N4O2S (C27 H28 N4 O2 S)

Compound Name

4,5-dimethyl-2-(4-methylphenyl)-6-[4-(naphthalene-2-sulfonyl)piperazin-1-yl]pyrimidine

IUPAC name

45-dimethyl-2-(4-methylphenyl)-6-[4-(naphthalene-2-sulfonyl)piperazin-1-yl]pyrimidine

SMILES

Cc(cc1)ccc1-c1nc(C)c(C)c(N(CC2)CCN2S(c2cc3ccccc3cc2)(=O)=O)n1

InChI

InChI=1S/C27H28N4O2S/c1-19-8-10-23(11-9-19)26-28-21(3)20(2)27(29-26)30-14-16-31(17-15-30)34(32,33)25-13-12-22-6-4-5-7-24(22)18-25/h4-13,18H,14-17H2,1-3H3

InChI Key

FCIDWDGLROWCIO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19851970

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

472.61

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.645

Distribution Coefficient, logD

6.261

Water Solubility, LogSw

-6.65

Polar Surface Area

53.748

Acid Dissociation Constant (pKa)

22.71

Base Dissociation Constant (pKb)

7.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

V014-8437 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with V014-8437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-8437?
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What is the minimum amount of V014-8437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-8437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-8437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-8437 available by request