V014-8663 Screening compound: N-{[4-(3-fluorophenyl)-1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}-2-methyl-N-(2-methylpropyl)propanamide

V014-8663 Screening compound: N-{[4-(3-fluorophenyl)-1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}-2-methyl-N-(2-methylpropyl)propanamide
V014-8663 Screening compound: N-{[4-(3-fluorophenyl)-1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}-2-methyl-N-(2-methylpropyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-8663
N-{[4-(3-fluorophenyl)-1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}-2-methyl-N-(2-methylpropyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-8663

Molecular Formula

C27H34F4N2O (C27 H34 F4 N2 O)

Compound Name

N-{[4-(3-fluorophenyl)-1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}-2-methyl-N-(2-methylpropyl)propanamide

IUPAC name

N-{[4-(3-fluorophenyl)-1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}-2-methyl-N-(2-methylpropyl)propanamide

SMILES

CC(C)CN(CC(CN(Cc1ccc(C(F)(F)F)cc1)C1)C1c1cccc(F)c1)C(C(C)C)=O

InChI

InChI=1S/C27H34F4N2O/c1-18(2)13-33(26(34)19(3)4)16-22-15-32(17-25(22)21-6-5-7-24(28)12-21)14-20-8-10-23(11-9-20)27(29,30)31/h5-12,18-19,22,25H,13-17H2,1-4H3

InChI Key

ZPIVUCUQUYZFHQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19979396

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

478.57

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.324

Distribution Coefficient, logD

4.030

Water Solubility, LogSw

-5.51

Polar Surface Area

20.415

Acid Dissociation Constant (pKa)

22.91

Base Dissociation Constant (pKb)

9.69

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

51.90

V014-8663 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with V014-8663 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-8663?
Check Price and Availability of V014-8663, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-8663 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-8663
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-8663
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-8663 available by request