V014-8666 Screening compound: 1-{4-[3-(2-chlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-yl]-1,4-diazepan-1-yl}-2-(thiophen-2-yl)ethan-1-one

V014-8666 Screening compound: 1-{4-[3-(2-chlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-yl]-1,4-diazepan-1-yl}-2-(thiophen-2-yl)ethan-1-one
V014-8666 Screening compound: 1-{4-[3-(2-chlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-yl]-1,4-diazepan-1-yl}-2-(thiophen-2-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-8666
1-{4-[3-(2-chlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-yl]-1,4-diazepan-1-yl}-2-(thiophen-2-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-8666

Molecular Formula

C26H23ClN6OS (C26 H23 ClN6 OS)

Compound Name

1-{4-[3-(2-chlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-yl]-1,4-diazepan-1-yl}-2-(thiophen-2-yl)ethan-1-one

IUPAC name

1-{4-[3-(2-chlorophenyl)-[124]triazolo[43-c]quinazolin-5-yl]-14-diazepan-1-yl}-2-(thiophen-2-yl)ethan-1-one

SMILES

O=C(Cc1cccs1)N(CCC1)CCN1c1nc(cccc2)c2c2nnc(-c(cccc3)c3Cl)n12

InChI

InChI=1S/C26H23ClN6OS/c27-21-10-3-1-8-19(21)24-29-30-25-20-9-2-4-11-22(20)28-26(33(24)25)32-13-6-12-31(14-15-32)23(34)17-18-7-5-16-35-18/h1-5,7-11,16H,6,12-15,17H2

InChI Key

RHASMLGILATUER-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19923672

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

503.03

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.638

Distribution Coefficient, logD

4.573

Water Solubility, LogSw

-4.84

Polar Surface Area

50.271

Acid Dissociation Constant (pKa)

21.18

Base Dissociation Constant (pKb)

6.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

V014-8666 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with V014-8666 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-8666?
Check Price and Availability of V014-8666, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V014-8666 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-8666
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-8666
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-8666 available by request