V014-8754 Screening compound: 3-chloro-N-[4-(4-ethylpiperazin-1-yl)-3-[(1,2,3,4-tetrahydronaphthalen-1-yl)sulfamoyl]phenyl]benzamide

V014-8754 Screening compound: 3-chloro-N-[4-(4-ethylpiperazin-1-yl)-3-[(1,2,3,4-tetrahydronaphthalen-1-yl)sulfamoyl]phenyl]benzamide
V014-8754 Screening compound: 3-chloro-N-[4-(4-ethylpiperazin-1-yl)-3-[(1,2,3,4-tetrahydronaphthalen-1-yl)sulfamoyl]phenyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V014-8754
3-chloro-N-[4-(4-ethylpiperazin-1-yl)-3-[(1,2,3,4-tetrahydronaphthalen-1-yl)sulfamoyl]phenyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V014-8754

Molecular Formula

C29H33ClN4O3S (C29 H33 ClN4 O3 S)

Compound Name

3-chloro-N-[4-(4-ethylpiperazin-1-yl)-3-[(1,2,3,4-tetrahydronaphthalen-1-yl)sulfamoyl]phenyl]benzamide

IUPAC name

3-chloro-N-[4-(4-ethylpiperazin-1-yl)-3-[(1234-tetrahydronaphthalen-1-yl)sulfamoyl]phenyl]benzamide

SMILES

CCN(CC1)CCN1c(ccc(NC(c1cccc(Cl)c1)=O)c1)c1S(NC(CCC1)c2c1cccc2)(=O)=O

InChI

InChI=1S/C29H33ClN4O3S/c1-2-33-15-17-34(18-16-33)27-14-13-24(31-29(35)22-9-5-10-23(30)19-22)20-28(27)38(36,37)32-26-12-6-8-21-7-3-4-11-25(21)26/h3-5,7,9-11,13-14,19-20,26,32H,2,6,8,12,15-18H2,1H3,(H,31,35)/t26-/m0/s1

InChI Key

ZIXAPYUCUBDXGX-SANMLTNESA-N

MDL Number (MFCD)

MFCD19972544

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

553.12

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.741

Distribution Coefficient, logD

5.280

Water Solubility, LogSw

-5.76

Polar Surface Area

71.833

Acid Dissociation Constant (pKa)

8.28

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.50

V014-8754 in Drug Discovery

Included in Screening Libraries

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V014-8754 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V014-8754?
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What is the minimum amount of V014-8754 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V014-8754
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V014-8754
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V014-8754 available by request