V015-0762 Screening compound: 1-[4-(4-fluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(2-thienyl)-1-ethanone

V015-0762 Screening compound: 1-[4-(4-fluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(2-thienyl)-1-ethanone
V015-0762 Screening compound: 1-[4-(4-fluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(2-thienyl)-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound V015-0762
1-[4-(4-fluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(2-thienyl)-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V015-0762

Molecular Formula

C24H26FN5O2S (C24 H26 FN5 O2 S)

Compound Name

1-[4-(4-fluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(2-thienyl)-1-ethanone

IUPAC name

1-[4-(4-fluorophenoxy)-2-(4-methylpiperazin-1-yl)-5H6H7H8H-pyrido[43-d]pyrimidin-6-yl]-2-(thiophen-2-yl)ethan-1-one

SMILES

CN(CC1)CCN1c1nc(Oc(cc2)ccc2F)c(CN(CC2)C(Cc3cccs3)=O)c2n1

InChI

InChI=1S/C24H26FN5O2S/c1-28-10-12-29(13-11-28)24-26-21-8-9-30(22(31)15-19-3-2-14-33-19)16-20(21)23(27-24)32-18-6-4-17(25)5-7-18/h2-7,14H,8-13,15-16H2,1H3

InChI Key

FAONAGWIOKZDTL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19908421

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

467.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.701

Distribution Coefficient, logD

3.129

Water Solubility, LogSw

-4.05

Polar Surface Area

50.473

Acid Dissociation Constant (pKa)

20.58

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

V015-0762 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

BRD4 Targeted Library (4534 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with V015-0762 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V015-0762?
Check Price and Availability of V015-0762, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V015-0762 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V015-0762
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V015-0762
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V015-0762 available by request