V015-4182 Screening compound: 1-[1-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine

V015-4182 Screening compound: 1-[1-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine
V015-4182 Screening compound: 1-[1-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound V015-4182
1-[1-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V015-4182

Molecular Formula

C27H21ClF3N5O3 (C27 H21 ClF3 N5 O3)

Compound Name

1-[1-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine

IUPAC name

1-[1-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carbonyl]-4-[3-(trifluoromethyl)phenyl]piperazine

SMILES

[O-][N+](c(cc1)ccc1-c(cc1C(N(CC2)CCN2c2cc(C(F)(F)F)ccc2)=O)nn1-c(cc1)ccc1Cl)=O

InChI

InChI=1S/C27H21ClF3N5O3/c28-20-6-10-21(11-7-20)35-25(17-24(32-35)18-4-8-22(9-5-18)36(38)39)26(37)34-14-12-33(13-15-34)23-3-1-2-19(16-23)27(29,30)31/h1-11,16-17H,12-15H2

InChI Key

GWLGMRJXJPSBLJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14242679

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

555.94

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

6.491

Distribution Coefficient, logD

6.491

Water Solubility, LogSw

-6.69

Polar Surface Area

66.352

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

1.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

V015-4182 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with V015-4182 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V015-4182?
Check Price and Availability of V015-4182, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V015-4182 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V015-4182
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V015-4182
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V015-4182 available by request