V016-4579 Screening compound: 4-chloro-N-{2-[(7-chloro-2-phenylquinazolin-4-yl)amino]ethyl}benzene-1-sulfonamide

V016-4579 Screening compound: 4-chloro-N-{2-[(7-chloro-2-phenylquinazolin-4-yl)amino]ethyl}benzene-1-sulfonamide
V016-4579 Screening compound: 4-chloro-N-{2-[(7-chloro-2-phenylquinazolin-4-yl)amino]ethyl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V016-4579
4-chloro-N-{2-[(7-chloro-2-phenylquinazolin-4-yl)amino]ethyl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V016-4579

Molecular Formula

C22H18Cl2N4O2S (C22 H18 Cl2 N4 O2 S)

Compound Name

4-chloro-N-{2-[(7-chloro-2-phenylquinazolin-4-yl)amino]ethyl}benzene-1-sulfonamide

IUPAC name

4-chloro-N-{2-[(7-chloro-2-phenylquinazolin-4-yl)amino]ethyl}benzene-1-sulfonamide

SMILES

O=S(c(cc1)ccc1Cl)(NCCNc1c(ccc(Cl)c2)c2nc(-c2ccccc2)n1)=O

InChI

InChI=1S/C22H18Cl2N4O2S/c23-16-6-9-18(10-7-16)31(29,30)26-13-12-25-22-19-11-8-17(24)14-20(19)27-21(28-22)15-4-2-1-3-5-15/h1-11,14,26H,12-13H2,(H,25,27,28)

InChI Key

PFBDXWHINSGJSY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19780735

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

473.38

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.670

Distribution Coefficient, logD

6.404

Water Solubility, LogSw

-6.65

Polar Surface Area

70.840

Acid Dissociation Constant (pKa)

10.99

Base Dissociation Constant (pKb)

7.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

V016-4579 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Others
  • Phosphatases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V016-4579 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V016-4579?
Check Price and Availability of V016-4579, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V016-4579 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V016-4579
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V016-4579
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V016-4579 available by request