V016-7910 Screening compound: 2-(4-chlorophenoxy)-N-{3-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}acetamide

V016-7910 Screening compound: 2-(4-chlorophenoxy)-N-{3-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}acetamide
V016-7910 Screening compound: 2-(4-chlorophenoxy)-N-{3-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V016-7910
2-(4-chlorophenoxy)-N-{3-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V016-7910

Molecular Formula

C23H17ClF2N2O3S (C23 H17 ClF2 N2 O3 S)

Compound Name

2-(4-chlorophenoxy)-N-{3-[3-(2,4-difluorophenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}acetamide

IUPAC name

2-(4-chlorophenoxy)-N-{3-[3-(24-difluorophenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}acetamide

SMILES

O=C(COc(cc1)ccc1Cl)Nc1cc(C(N2c(ccc(F)c3)c3F)SCC2=O)ccc1

InChI

InChI=1S/C23H17ClF2N2O3S/c24-15-4-7-18(8-5-15)31-12-21(29)27-17-3-1-2-14(10-17)23-28(22(30)13-32-23)20-9-6-16(25)11-19(20)26/h1-11,23H,12-13H2,(H,27,29)/t23-/m0/s1

InChI Key

AVRJYOWUOMRPOF-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19861568

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.92

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.773

Distribution Coefficient, logD

4.773

Water Solubility, LogSw

-5.09

Polar Surface Area

46.209

Acid Dissociation Constant (pKa)

12.31

Base Dissociation Constant (pKb)

1.54

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

V016-7910 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V016-7910 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V016-7910?
Check Price and Availability of V016-7910, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V016-7910 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V016-7910
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V016-7910
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V016-7910 available by request