V017-0052 Screening compound: N-(3-chlorophenyl)-1-[(3-methoxyphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V017-0052 Screening compound: N-(3-chlorophenyl)-1-[(3-methoxyphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V017-0052 Screening compound: N-(3-chlorophenyl)-1-[(3-methoxyphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V017-0052
N-(3-chlorophenyl)-1-[(3-methoxyphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V017-0052

Molecular Formula

C25H22ClN3O3S (C25 H22 ClN3 O3 S)

Compound Name

N-(3-chlorophenyl)-1-[(3-methoxyphenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

N-(3-chlorophenyl)-1-[(3-methoxyphenyl)methyl]-2-oxo-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

COc1cccc(CN(C(C23SCCN2C(Nc2cccc(Cl)c2)=O)=O)c2c3cccc2)c1

InChI

InChI=1S/C25H22ClN3O3S/c1-32-20-9-4-6-17(14-20)16-28-22-11-3-2-10-21(22)25(23(28)30)29(12-13-33-25)24(31)27-19-8-5-7-18(26)15-19/h2-11,14-15H,12-13,16H2,1H3,(H,27,31)/t25-/m0/s1

InChI Key

CYNAVIGHIBZRSQ-VWLOTQADSA-N

MDL Number (MFCD)

MFCD19871434

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.99

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.602

Distribution Coefficient, logD

5.602

Water Solubility, LogSw

-5.72

Polar Surface Area

47.944

Acid Dissociation Constant (pKa)

12.63

Base Dissociation Constant (pKb)

-0.02

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

V017-0052 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V017-0052 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V017-0052?
Check Price and Availability of V017-0052, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V017-0052 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V017-0052
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V017-0052
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V017-0052 available by request