V017-3244 Screening compound: 4-(2,4-difluorophenoxy)-2-(morpholin-4-yl)-N-phenyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

V017-3244 Screening compound: 4-(2,4-difluorophenoxy)-2-(morpholin-4-yl)-N-phenyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide
V017-3244 Screening compound: 4-(2,4-difluorophenoxy)-2-(morpholin-4-yl)-N-phenyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V017-3244
4-(2,4-difluorophenoxy)-2-(morpholin-4-yl)-N-phenyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V017-3244

Molecular Formula

C24H23F2N5O3 (C24 H23 F2 N5 O3)

Compound Name

4-(2,4-difluorophenoxy)-2-(morpholin-4-yl)-N-phenyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

IUPAC name

4-(24-difluorophenoxy)-2-(morpholin-4-yl)-N-phenyl-5H6H7H8H-pyrido[43-d]pyrimidine-6-carboxamide

SMILES

O=C(Nc1ccccc1)N(CC1)Cc2c1nc(N1CCOCC1)nc2Oc(ccc(F)c1)c1F

InChI

InChI=1S/C24H23F2N5O3/c25-16-6-7-21(19(26)14-16)34-22-18-15-31(24(32)27-17-4-2-1-3-5-17)9-8-20(18)28-23(29-22)30-10-12-33-13-11-30/h1-7,14H,8-13,15H2,(H,27,32)

InChI Key

IWGZAMURZOZQBP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19933439

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

467.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.956

Distribution Coefficient, logD

3.956

Water Solubility, LogSw

-4.21

Polar Surface Area

63.321

Acid Dissociation Constant (pKa)

14.23

Base Dissociation Constant (pKb)

3.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

V017-3244 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V017-3244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V017-3244?
Check Price and Availability of V017-3244, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V017-3244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V017-3244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V017-3244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V017-3244 available by request