V017-3245 Screening compound: 2-methoxy-6-{[4-(2-methoxyphenoxy)-2-(morpholin-4-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl]methyl}phenol

V017-3245 Screening compound: 2-methoxy-6-{[4-(2-methoxyphenoxy)-2-(morpholin-4-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl]methyl}phenol
V017-3245 Screening compound: 2-methoxy-6-{[4-(2-methoxyphenoxy)-2-(morpholin-4-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl]methyl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound V017-3245
2-methoxy-6-{[4-(2-methoxyphenoxy)-2-(morpholin-4-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl]methyl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V017-3245

Molecular Formula

C26H30N4O5 (C26 H30 N4 O5)

Compound Name

2-methoxy-6-{[4-(2-methoxyphenoxy)-2-(morpholin-4-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl]methyl}phenol

IUPAC name

2-methoxy-6-{[4-(2-methoxyphenoxy)-2-(morpholin-4-yl)-5H6H7H8H-pyrido[43-d]pyrimidin-6-yl]methyl}phenol

SMILES

COc(cccc1)c1Oc1c(CN(Cc(cccc2OC)c2O)CC2)c2nc(N2CCOCC2)n1

InChI

InChI=1S/C26H30N4O5/c1-32-21-7-3-4-8-22(21)35-25-19-17-29(16-18-6-5-9-23(33-2)24(18)31)11-10-20(19)27-26(28-25)30-12-14-34-15-13-30/h3-9,31H,10-17H2,1-2H3

InChI Key

ANUPQTJWWQRAMA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19932775

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

478.55

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.269

Distribution Coefficient, logD

4.246

Water Solubility, LogSw

-4.39

Polar Surface Area

72.325

Acid Dissociation Constant (pKa)

10.22

Base Dissociation Constant (pKb)

6.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

V017-3245 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with V017-3245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V017-3245?
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What is the minimum amount of V017-3245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V017-3245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V017-3245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V017-3245 available by request