V017-3268 Screening compound: 4-{6-[(3,5-dimethoxyphenyl)methyl]-4-(2-methoxyphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

V017-3268 Screening compound: 4-{6-[(3,5-dimethoxyphenyl)methyl]-4-(2-methoxyphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine
V017-3268 Screening compound: 4-{6-[(3,5-dimethoxyphenyl)methyl]-4-(2-methoxyphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound V017-3268
4-{6-[(3,5-dimethoxyphenyl)methyl]-4-(2-methoxyphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V017-3268

Molecular Formula

C27H32N4O5 (C27 H32 N4 O5)

Compound Name

4-{6-[(3,5-dimethoxyphenyl)methyl]-4-(2-methoxyphenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

IUPAC name

4-{6-[(35-dimethoxyphenyl)methyl]-4-(2-methoxyphenoxy)-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}morpholine

SMILES

COc1cc(CN(CCc2nc(N3CCOCC3)n3)Cc2c3Oc(cccc2)c2OC)cc(OC)c1

InChI

InChI=1S/C27H32N4O5/c1-32-20-14-19(15-21(16-20)33-2)17-30-9-8-23-22(18-30)26(36-25-7-5-4-6-24(25)34-3)29-27(28-23)31-10-12-35-13-11-31/h4-7,14-16H,8-13,17-18H2,1-3H3

InChI Key

LDAQKXRDRXPZQP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19932547

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

492.58

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.496

Distribution Coefficient, logD

3.909

Water Solubility, LogSw

-4.45

Polar Surface Area

64.303

Acid Dissociation Constant (pKa)

20.79

Base Dissociation Constant (pKb)

7.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.70

V017-3268 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V017-3268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V017-3268?
Check Price and Availability of V017-3268, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V017-3268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V017-3268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V017-3268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V017-3268 available by request