V017-3282 Screening compound: 1-[4-(3,4-difluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(4-fluorophenyl)-1-ethanone

V017-3282 Screening compound: 1-[4-(3,4-difluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(4-fluorophenyl)-1-ethanone
V017-3282 Screening compound: 1-[4-(3,4-difluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(4-fluorophenyl)-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound V017-3282
1-[4-(3,4-difluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(4-fluorophenyl)-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V017-3282

Molecular Formula

C26H26F3N5O2 (C26 H26 F3 N5 O2)

Compound Name

1-[4-(3,4-difluorophenoxy)-2-(4-methylpiperazino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]-2-(4-fluorophenyl)-1-ethanone

IUPAC name

1-[4-(34-difluorophenoxy)-2-(4-methylpiperazin-1-yl)-5H6H7H8H-pyrido[43-d]pyrimidin-6-yl]-2-(4-fluorophenyl)ethan-1-one

SMILES

CN(CC1)CCN1c1nc(CCN(C2)C(Cc(cc3)ccc3F)=O)c2c(Oc(cc2)cc(F)c2F)n1

InChI

InChI=1S/C26H26F3N5O2/c1-32-10-12-33(13-11-32)26-30-23-8-9-34(24(35)14-17-2-4-18(27)5-3-17)16-20(23)25(31-26)36-19-6-7-21(28)22(29)15-19/h2-7,15H,8-14,16H2,1H3

InChI Key

PREQJAUHDYFMIB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19933954

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

497.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.365

Distribution Coefficient, logD

3.793

Water Solubility, LogSw

-4.46

Polar Surface Area

49.455

Acid Dissociation Constant (pKa)

16.90

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.62

V017-3282 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

BRD4 Targeted Library (4534 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with V017-3282 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V017-3282?
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What is the minimum amount of V017-3282 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V017-3282
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V017-3282
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V017-3282 available by request