V018-1451 Screening compound: 2-{4-[(2,6-difluorobenzyl)oxy]phenyl}-N-(tetrahydro-2-furanylmethyl)-1,3-thiazole-4-carboxamide

V018-1451 Screening compound: 2-{4-[(2,6-difluorobenzyl)oxy]phenyl}-N-(tetrahydro-2-furanylmethyl)-1,3-thiazole-4-carboxamide
V018-1451 Screening compound: 2-{4-[(2,6-difluorobenzyl)oxy]phenyl}-N-(tetrahydro-2-furanylmethyl)-1,3-thiazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-1451
2-{4-[(2,6-difluorobenzyl)oxy]phenyl}-N-(tetrahydro-2-furanylmethyl)-1,3-thiazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-1451

Molecular Formula

C22H20F2N2O3S (C22 H20 F2 N2 O3 S)

Compound Name

2-{4-[(2,6-difluorobenzyl)oxy]phenyl}-N-(tetrahydro-2-furanylmethyl)-1,3-thiazole-4-carboxamide

IUPAC name

2-{4-[(26-difluorophenyl)methoxy]phenyl}-N-[(oxolan-2-yl)methyl]-13-thiazole-4-carboxamide

SMILES

O=C(c1csc(-c(cc2)ccc2OCc(c(F)ccc2)c2F)n1)NCC1OCCC1

InChI

InChI=1S/C22H20F2N2O3S/c23-18-4-1-5-19(24)17(18)12-29-15-8-6-14(7-9-15)22-26-20(13-30-22)21(27)25-11-16-3-2-10-28-16/h1,4-9,13,16H,2-3,10-12H2,(H,25,27)/t16-/m1/s1

InChI Key

XNYMRQAJCQATPD-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD19925378

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.079

Distribution Coefficient, logD

4.079

Water Solubility, LogSw

-4.32

Polar Surface Area

50.268

Acid Dissociation Constant (pKa)

14.22

Base Dissociation Constant (pKb)

-3.33

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.27

References: we are preparing a list of scientific research reports with V018-1451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-1451?
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What is the minimum amount of V018-1451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-1451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-1451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-1451 available by request