V018-1478 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[5-hydroxy-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

V018-1478 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[5-hydroxy-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
V018-1478 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[5-hydroxy-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-1478
1-[(4-fluorophenyl)methyl]-3-[5-hydroxy-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-1478

Molecular Formula

C29H18F4N4O3 (C29 H18 F4 N4 O3)

Compound Name

1-[(4-fluorophenyl)methyl]-3-[5-hydroxy-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

IUPAC name

1-[(4-fluorophenyl)methyl]-3-[5-hydroxy-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-4-(1H-indol-3-yl)-25-dihydro-1H-pyrrole-25-dione

SMILES

Oc(n(-c1ccccc1)nc1C(F)(F)F)c1C(C(N1Cc(cc2)ccc2F)=O)=C(c2c[nH]c3c2cccc3)C1=O

InChI

InChI=1S/C29H18F4N4O3/c30-17-12-10-16(11-13-17)15-36-26(38)22(20-14-34-21-9-5-4-8-19(20)21)23(27(36)39)24-25(29(31,32)33)35-37(28(24)40)18-6-2-1-3-7-18/h1-14,34,40H,15H2

InChI Key

XEDLYEAIRIQPCV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19972398

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

546.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.892

Distribution Coefficient, logD

1.146

Water Solubility, LogSw

-4.75

Polar Surface Area

69.134

Acid Dissociation Constant (pKa)

3.65

Base Dissociation Constant (pKb)

-2.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.90

V018-1478 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Nucleoside Mimetics Library (2197 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Antiviral
  • Infections
  • Cancer
  • Immune system

References: we are preparing a list of scientific research reports with V018-1478 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-1478?
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What is the minimum amount of V018-1478 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-1478
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-1478
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-1478 available by request