V018-3447 Screening compound: ethyl 3-[(cyclopropylcarbamoyl)methyl]-5-(2,3-dimethoxyphenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

V018-3447 Screening compound: ethyl 3-[(cyclopropylcarbamoyl)methyl]-5-(2,3-dimethoxyphenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
V018-3447 Screening compound: ethyl 3-[(cyclopropylcarbamoyl)methyl]-5-(2,3-dimethoxyphenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-3447
ethyl 3-[(cyclopropylcarbamoyl)methyl]-5-(2,3-dimethoxyphenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-3447

Molecular Formula

C23H27N3O5S (C23 H27 N3 O5 S)

Compound Name

ethyl 3-[(cyclopropylcarbamoyl)methyl]-5-(2,3-dimethoxyphenyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

IUPAC name

ethyl 3-[(cyclopropylcarbamoyl)methyl]-5-(23-dimethoxyphenyl)-7-methyl-5H-[13]thiazolo[32-a]pyrimidine-6-carboxylate

SMILES

CCOC(C1=C(C)N=C2SC=C(CC(NC3CC3)=O)N2C1c(cccc1OC)c1OC)=O

InChI

InChI=1S/C23H27N3O5S/c1-5-31-22(28)19-13(2)24-23-26(15(12-32-23)11-18(27)25-14-9-10-14)20(19)16-7-6-8-17(29-3)21(16)30-4/h6-8,12,14,20H,5,9-11H2,1-4H3,(H,25,27)/t20-/m1/s1

InChI Key

ZOMVNSWRLGWWMF-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD19825762

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.866

Distribution Coefficient, logD

2.865

Water Solubility, LogSw

-3.22

Polar Surface Area

72.014

Acid Dissociation Constant (pKa)

13.86

Base Dissociation Constant (pKb)

4.72

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

V018-3447 in Drug Discovery

Included in Screening Libraries

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with V018-3447 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-3447?
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What is the minimum amount of V018-3447 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-3447
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-3447
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-3447 available by request