V018-4348 Screening compound: 1-{4-[(7-chloro-2-phenylimidazo[2,1-b][1,3]benzothiazol-3-yl)methyl]piperazino}-1-propanone

V018-4348 Screening compound: 1-{4-[(7-chloro-2-phenylimidazo[2,1-b][1,3]benzothiazol-3-yl)methyl]piperazino}-1-propanone
V018-4348 Screening compound: 1-{4-[(7-chloro-2-phenylimidazo[2,1-b][1,3]benzothiazol-3-yl)methyl]piperazino}-1-propanone alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-4348
1-{4-[(7-chloro-2-phenylimidazo[2,1-b][1,3]benzothiazol-3-yl)methyl]piperazino}-1-propanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-4348

Molecular Formula

C23H23ClN4OS (C23 H23 ClN4 OS)

Compound Name

1-{4-[(7-chloro-2-phenylimidazo[2,1-b][1,3]benzothiazol-3-yl)methyl]piperazino}-1-propanone

IUPAC name

1-[4-({10-chloro-4-phenyl-7-thia-25-diazatricyclo[6.4.0.0^{26}]dodeca-1(8)35911-pentaen-3-yl}methyl)piperazin-1-yl]propan-1-one

SMILES

CCC(N1CCN(Cc2c(-c3ccccc3)nc3sc(cc(cc4)Cl)c4n23)CC1)=O

InChI

InChI=1S/C23H23ClN4OS/c1-2-21(29)27-12-10-26(11-13-27)15-19-22(16-6-4-3-5-7-16)25-23-28(19)18-9-8-17(24)14-20(18)30-23/h3-9,14H,2,10-13,15H2,1H3

InChI Key

WLJMJSGEHPLIKC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19783509

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

438.98

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.308

Distribution Coefficient, logD

4.300

Water Solubility, LogSw

-4.42

Polar Surface Area

28.686

Acid Dissociation Constant (pKa)

24.10

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

V018-4348 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with V018-4348 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-4348?
Check Price and Availability of V018-4348, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V018-4348 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-4348
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-4348
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-4348 available by request