V018-5423 Screening compound: 2-[CYCLOHEXYL(METHYL)AMINO]-4-(MORPHOLIN-4-YL)-N-PHENYL-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDINE-6-CARBOXAMIDE

V018-5423 Screening compound: 2-[CYCLOHEXYL(METHYL)AMINO]-4-(MORPHOLIN-4-YL)-N-PHENYL-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDINE-6-CARBOXAMIDE
V018-5423 Screening compound: 2-[CYCLOHEXYL(METHYL)AMINO]-4-(MORPHOLIN-4-YL)-N-PHENYL-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDINE-6-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-5423
2-[CYCLOHEXYL(METHYL)AMINO]-4-(MORPHOLIN-4-YL)-N-PHENYL-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDINE-6-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-5423

Molecular Formula

C25H34N6O2 (C25 H34 N6 O2)

Compound Name

2-[CYCLOHEXYL(METHYL)AMINO]-4-(MORPHOLIN-4-YL)-N-PHENYL-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDINE-6-CARBOXAMIDE

IUPAC name

n/a

SMILES

CN(C1CCCCC1)c1nc(N2CCOCC2)c(CN(CC2)C(Nc3ccccc3)=O)c2n1

InChI

InChI=1S/C25H34N6O2/c1-29(20-10-6-3-7-11-20)24-27-22-12-13-31(25(32)26-19-8-4-2-5-9-19)18-21(22)23(28-24)30-14-16-33-17-15-30/h2,4-5,8-9,20H,3,6-7,10-18H2,1H3,(H,26,32)

InChI Key

OTUCLZFFDHDWAU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19908907

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

450.58

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.833

Distribution Coefficient, logD

3.374

Water Solubility, LogSw

-3.91

Polar Surface Area

57.669

Acid Dissociation Constant (pKa)

14.01

Base Dissociation Constant (pKb)

10.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.00

V018-5423 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V018-5423 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-5423?
Check Price and Availability of V018-5423, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V018-5423 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-5423
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-5423
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-5423 available by request