V018-5448 Screening compound: 6-(benzenesulfonyl)-2-(4-cyclohexylpiperazin-1-yl)-N,N-dimethyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

V018-5448 Screening compound: 6-(benzenesulfonyl)-2-(4-cyclohexylpiperazin-1-yl)-N,N-dimethyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine
V018-5448 Screening compound: 6-(benzenesulfonyl)-2-(4-cyclohexylpiperazin-1-yl)-N,N-dimethyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-5448
6-(benzenesulfonyl)-2-(4-cyclohexylpiperazin-1-yl)-N,N-dimethyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-5448

Molecular Formula

C25H36N6O2S (C25 H36 N6 O2 S)

Compound Name

6-(benzenesulfonyl)-2-(4-cyclohexylpiperazin-1-yl)-N,N-dimethyl-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

IUPAC name

6-(benzenesulfonyl)-2-(4-cyclohexylpiperazin-1-yl)-NN-dimethyl-5H6H7H8H-pyrido[43-d]pyrimidin-4-amine

SMILES

CN(C)c1c(CN(CC2)S(c3ccccc3)(=O)=O)c2nc(N(CC2)CCN2C2CCCCC2)n1

InChI

InChI=1S/C25H36N6O2S/c1-28(2)24-22-19-31(34(32,33)21-11-7-4-8-12-21)14-13-23(22)26-25(27-24)30-17-15-29(16-18-30)20-9-5-3-6-10-20/h4,7-8,11-12,20H,3,5-6,9-10,13-19H2,1-2H3

InChI Key

FVYRDENHUZWUPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19908891

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

484.67

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.110

Distribution Coefficient, logD

3.454

Water Solubility, LogSw

-4.10

Polar Surface Area

59.894

Acid Dissociation Constant (pKa)

20.31

Base Dissociation Constant (pKb)

7.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

V018-5448 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V018-5448 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-5448?
Check Price and Availability of V018-5448, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V018-5448 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-5448
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-5448
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-5448 available by request