V018-7748 Screening compound: 8-(4-chlorobenzenesulfonyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one

V018-7748 Screening compound: 8-(4-chlorobenzenesulfonyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one
V018-7748 Screening compound: 8-(4-chlorobenzenesulfonyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V018-7748
8-(4-chlorobenzenesulfonyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V018-7748

Molecular Formula

C21H21ClF3N3O3S (C21 H21 ClF3 N3 O3 S)

Compound Name

8-(4-chlorobenzenesulfonyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-1,4,8-triazaspiro[4.5]decan-2-one

IUPAC name

8-(4-chlorobenzenesulfonyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-148-triazaspiro[4.5]decan-2-one

SMILES

O=C1N(Cc2cc(C(F)(F)F)ccc2)C(CC2)(CCN2S(c(cc2)ccc2Cl)(=O)=O)NC1

InChI

InChI=1S/C21H21ClF3N3O3S/c22-17-4-6-18(7-5-17)32(30,31)27-10-8-20(9-11-27)26-13-19(29)28(20)14-15-2-1-3-16(12-15)21(23,24)25/h1-7,12,26H,8-11,13-14H2

InChI Key

RVZZQTVSFVPKQF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19816697

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

487.93

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.922

Distribution Coefficient, logD

3.832

Water Solubility, LogSw

-4.51

Polar Surface Area

59.897

Acid Dissociation Constant (pKa)

18.06

Base Dissociation Constant (pKb)

6.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

V018-7748 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with V018-7748 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V018-7748?
Check Price and Availability of V018-7748, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V018-7748 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V018-7748
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V018-7748
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V018-7748 available by request