V019-0355 Screening compound: 5-(2-chlorobenzamido)-1-[(3-fluorophenyl)methyl]-N-[4-(trifluoromethyl)phenyl]-1H-indole-2-carboxamide

V019-0355 Screening compound: 5-(2-chlorobenzamido)-1-[(3-fluorophenyl)methyl]-N-[4-(trifluoromethyl)phenyl]-1H-indole-2-carboxamide
V019-0355 Screening compound: 5-(2-chlorobenzamido)-1-[(3-fluorophenyl)methyl]-N-[4-(trifluoromethyl)phenyl]-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V019-0355
5-(2-chlorobenzamido)-1-[(3-fluorophenyl)methyl]-N-[4-(trifluoromethyl)phenyl]-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V019-0355

Molecular Formula

C30H20ClF4N3O2 (C30 H20 ClF4 N3 O2)

Compound Name

5-(2-chlorobenzamido)-1-[(3-fluorophenyl)methyl]-N-[4-(trifluoromethyl)phenyl]-1H-indole-2-carboxamide

IUPAC name

5-(2-chlorobenzamido)-1-[(3-fluorophenyl)methyl]-N-[4-(trifluoromethyl)phenyl]-1H-indole-2-carboxamide

SMILES

O=C(c1cc(cc(cc2)NC(c(cccc3)c3Cl)=O)c2n1Cc1cc(F)ccc1)Nc1ccc(C(F)(F)F)cc1

InChI

InChI=1S/C30H20ClF4N3O2/c31-25-7-2-1-6-24(25)28(39)37-23-12-13-26-19(15-23)16-27(38(26)17-18-4-3-5-21(32)14-18)29(40)36-22-10-8-20(9-11-22)30(33,34)35/h1-16H,17H2,(H,36,40)(H,37,39)

InChI Key

MLHVJQSGEDHUKC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19782263

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

565.95

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.619

Distribution Coefficient, logD

7.619

Water Solubility, LogSw

-6.51

Polar Surface Area

46.875

Acid Dissociation Constant (pKa)

10.88

Base Dissociation Constant (pKb)

-2.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

V019-0355 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V019-0355 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V019-0355?
Check Price and Availability of V019-0355, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V019-0355 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V019-0355
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V019-0355
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V019-0355 available by request