V019-1497 Screening compound: 4-(2,4-difluorophenoxy)-N-(3-methoxyphenyl)-2-(piperidin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

V019-1497 Screening compound: 4-(2,4-difluorophenoxy)-N-(3-methoxyphenyl)-2-(piperidin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide
V019-1497 Screening compound: 4-(2,4-difluorophenoxy)-N-(3-methoxyphenyl)-2-(piperidin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V019-1497
4-(2,4-difluorophenoxy)-N-(3-methoxyphenyl)-2-(piperidin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V019-1497

Molecular Formula

C26H27F2N5O3 (C26 H27 F2 N5 O3)

Compound Name

4-(2,4-difluorophenoxy)-N-(3-methoxyphenyl)-2-(piperidin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

IUPAC name

4-(24-difluorophenoxy)-N-(3-methoxyphenyl)-2-(piperidin-1-yl)-5H6H7H8H-pyrido[43-d]pyrimidine-6-carboxamide

SMILES

COc1cccc(NC(N(CC2)Cc3c2nc(N2CCCCC2)nc3Oc(ccc(F)c2)c2F)=O)c1

InChI

InChI=1S/C26H27F2N5O3/c1-35-19-7-5-6-18(15-19)29-26(34)33-13-10-22-20(16-33)24(36-23-9-8-17(27)14-21(23)28)31-25(30-22)32-11-3-2-4-12-32/h5-9,14-15H,2-4,10-13,16H2,1H3,(H,29,34)

InChI Key

HWHBPTDAGWOJRH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19933444

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

495.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.373

Distribution Coefficient, logD

5.373

Water Solubility, LogSw

-5.35

Polar Surface Area

62.957

Acid Dissociation Constant (pKa)

13.25

Base Dissociation Constant (pKb)

3.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.62

V019-1497 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer

References: we are preparing a list of scientific research reports with V019-1497 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V019-1497?
Check Price and Availability of V019-1497, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V019-1497 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V019-1497
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V019-1497
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V019-1497 available by request