V019-3238 Screening compound: 4-[4-(4-fluoro-3-methylphenoxy)-6-[3-(trifluoromethyl)benzoyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine

V019-3238 Screening compound: 4-[4-(4-fluoro-3-methylphenoxy)-6-[3-(trifluoromethyl)benzoyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine
V019-3238 Screening compound: 4-[4-(4-fluoro-3-methylphenoxy)-6-[3-(trifluoromethyl)benzoyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound V019-3238
4-[4-(4-fluoro-3-methylphenoxy)-6-[3-(trifluoromethyl)benzoyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V019-3238

Molecular Formula

C26H24F4N4O3 (C26 H24 F4 N4 O3)

Compound Name

4-[4-(4-fluoro-3-methylphenoxy)-6-[3-(trifluoromethyl)benzoyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]morpholine

IUPAC name

4-[4-(4-fluoro-3-methylphenoxy)-6-[3-(trifluoromethyl)benzoyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]morpholine

SMILES

Cc(cc(cc1)Oc2nc(N3CCOCC3)nc(CC3)c2CN3C(c2cc(C(F)(F)F)ccc2)=O)c1F

InChI

InChI=1S/C26H24F4N4O3/c1-16-13-19(5-6-21(16)27)37-23-20-15-34(24(35)17-3-2-4-18(14-17)26(28,29)30)8-7-22(20)31-25(32-23)33-9-11-36-12-10-33/h2-6,13-14H,7-12,15H2,1H3

InChI Key

NWEMQKFOOKAXQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19933986

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

516.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.916

Distribution Coefficient, logD

4.916

Water Solubility, LogSw

-4.81

Polar Surface Area

54.414

Acid Dissociation Constant (pKa)

20.15

Base Dissociation Constant (pKb)

1.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

V019-3238 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V019-3238 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V019-3238?
Check Price and Availability of V019-3238, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V019-3238 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V019-3238
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V019-3238
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V019-3238 available by request