V019-4448 Screening compound: {2-[(2,4-difluorophenoxy)methyl]-1,3-thiazol-4-yl}(4-methylpiperazino)methanone

V019-4448 Screening compound: {2-[(2,4-difluorophenoxy)methyl]-1,3-thiazol-4-yl}(4-methylpiperazino)methanone
V019-4448 Screening compound: {2-[(2,4-difluorophenoxy)methyl]-1,3-thiazol-4-yl}(4-methylpiperazino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound V019-4448
{2-[(2,4-difluorophenoxy)methyl]-1,3-thiazol-4-yl}(4-methylpiperazino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V019-4448

Molecular Formula

C16H17F2N3O2S (C16 H17 F2 N3 O2 S)

Compound Name

{2-[(2,4-difluorophenoxy)methyl]-1,3-thiazol-4-yl}(4-methylpiperazino)methanone

IUPAC name

1-{2-[(24-difluorophenoxy)methyl]-13-thiazole-4-carbonyl}-4-methylpiperazine

SMILES

CN(CC1)CCN1C(c1csc(COc(ccc(F)c2)c2F)n1)=O

InChI

InChI=1S/C16H17F2N3O2S/c1-20-4-6-21(7-5-20)16(22)13-10-24-15(19-13)9-23-14-3-2-11(17)8-12(14)18/h2-3,8,10H,4-7,9H2,1H3

InChI Key

XLMCEXXTOVSHOS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19832735

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

353.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.195

Distribution Coefficient, logD

2.063

Water Solubility, LogSw

-2.77

Polar Surface Area

38.178

Acid Dissociation Constant (pKa)

28.88

Base Dissociation Constant (pKb)

6.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

V019-4448 in Drug Discovery

Included in Screening Libraries

NOTUM (Wnt signaling) Library (3881 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with V019-4448 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V019-4448?
Check Price and Availability of V019-4448, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V019-4448 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V019-4448
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V019-4448
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V019-4448 available by request