V019-6012 Screening compound: 1-[8-CHLORO-3-(THIOPHEN-2-YL)-[1,2,4]TRIAZOLO[4,3-C]QUINAZOLIN-5-YL]-4-(2-FLUOROBENZOYL)PIPERAZINE

V019-6012 Screening compound: 1-[8-CHLORO-3-(THIOPHEN-2-YL)-[1,2,4]TRIAZOLO[4,3-C]QUINAZOLIN-5-YL]-4-(2-FLUOROBENZOYL)PIPERAZINE
V019-6012 Screening compound: 1-[8-CHLORO-3-(THIOPHEN-2-YL)-[1,2,4]TRIAZOLO[4,3-C]QUINAZOLIN-5-YL]-4-(2-FLUOROBENZOYL)PIPERAZINE alternative view

Chemical Structure Depiction of ChemDiv screening compound V019-6012
1-[8-CHLORO-3-(THIOPHEN-2-YL)-[1,2,4]TRIAZOLO[4,3-C]QUINAZOLIN-5-YL]-4-(2-FLUOROBENZOYL)PIPERAZINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V019-6012

Molecular Formula

C24H18ClFN6OS (C24 H18 ClFN6 OS)

Compound Name

1-[8-CHLORO-3-(THIOPHEN-2-YL)-[1,2,4]TRIAZOLO[4,3-C]QUINAZOLIN-5-YL]-4-(2-FLUOROBENZOYL)PIPERAZINE

IUPAC name

n/a

SMILES

O=C(c(cccc1)c1F)N(CC1)CCN1c1nc(cc(cc2)Cl)c2c2nnc(-c3cccs3)n12

InChI

InChI=1S/C24H18ClFN6OS/c25-15-7-8-17-19(14-15)27-24(32-21(17)28-29-22(32)20-6-3-13-34-20)31-11-9-30(10-12-31)23(33)16-4-1-2-5-18(16)26/h1-8,13-14H,9-12H2

InChI Key

WKDKKZWTIRXOBI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19923227

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

492.96

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.069

Distribution Coefficient, logD

5.030

Water Solubility, LogSw

-5.22

Polar Surface Area

50.468

Acid Dissociation Constant (pKa)

20.97

Base Dissociation Constant (pKb)

6.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

V019-6012 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer

References: we are preparing a list of scientific research reports with V019-6012 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V019-6012?
Check Price and Availability of V019-6012, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V019-6012 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V019-6012
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V019-6012
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V019-6012 available by request