V019-9377 Screening compound: 4-chloro-N-({2-[(4-fluorophenyl)methanesulfonyl]-1-[(oxolan-2-yl)methyl]-1H-imidazol-5-yl}methyl)-N-(2-methylpropyl)benzene-1-sulfonamide

V019-9377 Screening compound: 4-chloro-N-({2-[(4-fluorophenyl)methanesulfonyl]-1-[(oxolan-2-yl)methyl]-1H-imidazol-5-yl}methyl)-N-(2-methylpropyl)benzene-1-sulfonamide
V019-9377 Screening compound: 4-chloro-N-({2-[(4-fluorophenyl)methanesulfonyl]-1-[(oxolan-2-yl)methyl]-1H-imidazol-5-yl}methyl)-N-(2-methylpropyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V019-9377
4-chloro-N-({2-[(4-fluorophenyl)methanesulfonyl]-1-[(oxolan-2-yl)methyl]-1H-imidazol-5-yl}methyl)-N-(2-methylpropyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V019-9377

Molecular Formula

C26H31ClFN3O5S2 (C26 H31 ClFN3 O5 S2)

Compound Name

4-chloro-N-({2-[(4-fluorophenyl)methanesulfonyl]-1-[(oxolan-2-yl)methyl]-1H-imidazol-5-yl}methyl)-N-(2-methylpropyl)benzene-1-sulfonamide

IUPAC name

4-chloro-N-({2-[(4-fluorophenyl)methanesulfonyl]-1-[(oxolan-2-yl)methyl]-1H-imidazol-5-yl}methyl)-N-(2-methylpropyl)benzene-1-sulfonamide

SMILES

CC(C)CN(Cc(n1CC2OCCC2)cnc1S(Cc(cc1)ccc1F)(=O)=O)S(c(cc1)ccc1Cl)(=O)=O

InChI

InChI=1S/C26H31ClFN3O5S2/c1-19(2)15-30(38(34,35)25-11-7-21(27)8-12-25)16-23-14-29-26(31(23)17-24-4-3-13-36-24)37(32,33)18-20-5-9-22(28)10-6-20/h5-12,14,19,24H,3-4,13,15-18H2,1-2H3/t24-/m1/s1

InChI Key

PJUOOGOAOWJDQF-XMMPIXPASA-N

MDL Number (MFCD)

MFCD19823386

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

584.13

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.417

Distribution Coefficient, logD

4.417

Water Solubility, LogSw

-4.47

Polar Surface Area

80.681

Acid Dissociation Constant (pKa)

19.56

Base Dissociation Constant (pKb)

-3.04

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.30

V019-9377 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V019-9377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V019-9377?
Check Price and Availability of V019-9377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V019-9377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V019-9377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V019-9377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V019-9377 available by request