V020-2714 Screening compound: 1-[(2,5-dichlorophenyl)sulfonyl]-8'-methyl-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one

V020-2714 Screening compound: 1-[(2,5-dichlorophenyl)sulfonyl]-8'-methyl-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one
V020-2714 Screening compound: 1-[(2,5-dichlorophenyl)sulfonyl]-8'-methyl-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V020-2714
1-[(2,5-dichlorophenyl)sulfonyl]-8'-methyl-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V020-2714

Molecular Formula

C19H19Cl2N3O3S (C19 H19 Cl2 N3 O3 S)

Compound Name

1-[(2,5-dichlorophenyl)sulfonyl]-8'-methyl-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one

IUPAC name

1-(25-dichlorobenzenesulfonyl)-8'-methyl-3'4'-dihydro-1'H-spiro[piperidine-42'-quinazolin]-4'-one

SMILES

Cc1cccc2c1NC(CC1)(CCN1S(c(cc(cc1)Cl)c1Cl)(=O)=O)NC2=O

InChI

InChI=1S/C19H19Cl2N3O3S/c1-12-3-2-4-14-17(12)22-19(23-18(14)25)7-9-24(10-8-19)28(26,27)16-11-13(20)5-6-15(16)21/h2-6,11,22H,7-10H2,1H3,(H,23,25)

InChI Key

UKBSVGVTJSJUHC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19939256

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.35

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.248

Distribution Coefficient, logD

3.248

Water Solubility, LogSw

-3.83

Polar Surface Area

66.009

Acid Dissociation Constant (pKa)

13.85

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

V020-2714 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V020-2714 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V020-2714?
Check Price and Availability of V020-2714, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V020-2714 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V020-2714
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V020-2714
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V020-2714 available by request