V020-2758 Screening compound: 6-(4-fluorobenzenesulfonyl)-N,N-dimethyl-2-[4-(4-methylphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

V020-2758 Screening compound: 6-(4-fluorobenzenesulfonyl)-N,N-dimethyl-2-[4-(4-methylphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine
V020-2758 Screening compound: 6-(4-fluorobenzenesulfonyl)-N,N-dimethyl-2-[4-(4-methylphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound V020-2758
6-(4-fluorobenzenesulfonyl)-N,N-dimethyl-2-[4-(4-methylphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V020-2758

Molecular Formula

C26H31FN6O2S (C26 H31 FN6 O2 S)

Compound Name

6-(4-fluorobenzenesulfonyl)-N,N-dimethyl-2-[4-(4-methylphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-amine

IUPAC name

6-(4-fluorobenzenesulfonyl)-NN-dimethyl-2-[4-(4-methylphenyl)piperazin-1-yl]-5H6H7H8H-pyrido[43-d]pyrimidin-4-amine

SMILES

Cc(cc1)ccc1N(CC1)CCN1c1nc(N(C)C)c(CN(CC2)S(c(cc3)ccc3F)(=O)=O)c2n1

InChI

InChI=1S/C26H31FN6O2S/c1-19-4-8-21(9-5-19)31-14-16-32(17-15-31)26-28-24-12-13-33(18-23(24)25(29-26)30(2)3)36(34,35)22-10-6-20(27)7-11-22/h4-11H,12-18H2,1-3H3

InChI Key

GBPLPYBQOOJPOI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19933169

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

510.64

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.847

Distribution Coefficient, logD

4.744

Water Solubility, LogSw

-4.57

Polar Surface Area

60.061

Acid Dissociation Constant (pKa)

20.31

Base Dissociation Constant (pKb)

6.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

V020-2758 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with V020-2758 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V020-2758?
Check Price and Availability of V020-2758, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V020-2758 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V020-2758
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V020-2758
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V020-2758 available by request