V020-3418 Screening compound: 1-[4-(4-fluorophenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]-4-methylpiperidine

V020-3418 Screening compound: 1-[4-(4-fluorophenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]-4-methylpiperidine
V020-3418 Screening compound: 1-[4-(4-fluorophenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]-4-methylpiperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V020-3418
1-[4-(4-fluorophenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]-4-methylpiperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V020-3418

Molecular Formula

C24H27FN4OS (C24 H27 FN4 OS)

Compound Name

1-[4-(4-fluorophenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]-4-methylpiperidine

IUPAC name

1-[4-(4-fluorophenoxy)-6-[(thiophen-3-yl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]-4-methylpiperidine

SMILES

CC(CC1)CCN1c1nc(Oc(cc2)ccc2F)c(CN(Cc2cscc2)CC2)c2n1

InChI

InChI=1S/C24H27FN4OS/c1-17-6-11-29(12-7-17)24-26-22-8-10-28(14-18-9-13-31-16-18)15-21(22)23(27-24)30-20-4-2-19(25)3-5-20/h2-5,9,13,16-17H,6-8,10-12,14-15H2,1H3

InChI Key

ILTWPBYYDVJMQM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19932720

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

438.57

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.705

Distribution Coefficient, logD

5.692

Water Solubility, LogSw

-5.49

Polar Surface Area

34.608

Acid Dissociation Constant (pKa)

20.19

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.67

V020-3418 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with V020-3418 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V020-3418?
Check Price and Availability of V020-3418, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V020-3418 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V020-3418
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V020-3418
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V020-3418 available by request