V020-4777 Screening compound: 2-{[4-(diphenylmethyl)piperazin-1-yl]methyl}-N-(4-fluorophenyl)-1,3-oxazole-4-carboxamide

V020-4777 Screening compound: 2-{[4-(diphenylmethyl)piperazin-1-yl]methyl}-N-(4-fluorophenyl)-1,3-oxazole-4-carboxamide
V020-4777 Screening compound: 2-{[4-(diphenylmethyl)piperazin-1-yl]methyl}-N-(4-fluorophenyl)-1,3-oxazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V020-4777
2-{[4-(diphenylmethyl)piperazin-1-yl]methyl}-N-(4-fluorophenyl)-1,3-oxazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V020-4777

Molecular Formula

C28H27FN4O2 (C28 H27 FN4 O2)

Compound Name

2-{[4-(diphenylmethyl)piperazin-1-yl]methyl}-N-(4-fluorophenyl)-1,3-oxazole-4-carboxamide

IUPAC name

2-{[4-(diphenylmethyl)piperazin-1-yl]methyl}-N-(4-fluorophenyl)-13-oxazole-4-carboxamide

SMILES

O=C(c1coc(CN(CC2)CCN2C(c2ccccc2)c2ccccc2)n1)Nc(cc1)ccc1F

InChI

InChI=1S/C28H27FN4O2/c29-23-11-13-24(14-12-23)30-28(34)25-20-35-26(31-25)19-32-15-17-33(18-16-32)27(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-14,20,27H,15-19H2,(H,30,34)

InChI Key

HBBOQSXPYWMOMZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19914320

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

470.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.648

Distribution Coefficient, logD

4.604

Water Solubility, LogSw

-4.53

Polar Surface Area

48.029

Acid Dissociation Constant (pKa)

10.21

Base Dissociation Constant (pKb)

6.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

V020-4777 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

DGK Inhibitors Library (10558 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
Targets:
  • Kinases
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with V020-4777 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V020-4777?
Check Price and Availability of V020-4777, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V020-4777 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V020-4777
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V020-4777
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V020-4777 available by request