V020-8044 Screening compound: 1-[4-(3-methoxyphenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

V020-8044 Screening compound: 1-[4-(3-methoxyphenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine
V020-8044 Screening compound: 1-[4-(3-methoxyphenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V020-8044
1-[4-(3-methoxyphenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V020-8044

Molecular Formula

C24H28N4O2S (C24 H28 N4 O2 S)

Compound Name

1-[4-(3-methoxyphenoxy)-6-[(thiophen-3-yl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

IUPAC name

1-[4-(3-methoxyphenoxy)-6-[(thiophen-3-yl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]piperidine

SMILES

COc1cccc(Oc2c(CN(Cc3cscc3)CC3)c3nc(N3CCCCC3)n2)c1

InChI

InChI=1S/C24H28N4O2S/c1-29-19-6-5-7-20(14-19)30-23-21-16-27(15-18-9-13-31-17-18)12-8-22(21)25-24(26-23)28-10-3-2-4-11-28/h5-7,9,13-14,17H,2-4,8,10-12,15-16H2,1H3

InChI Key

KTSWCXDGRWZKEM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19932756

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

436.58

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.307

Distribution Coefficient, logD

5.294

Water Solubility, LogSw

-5.28

Polar Surface Area

42.152

Acid Dissociation Constant (pKa)

20.48

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

V020-8044 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with V020-8044 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V020-8044?
Check Price and Availability of V020-8044, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V020-8044 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V020-8044
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V020-8044
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V020-8044 available by request