V021-0227 Screening compound: 1-[6-(3-chlorobenzenesulfonyl)-4-(3,4-difluorophenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

V021-0227 Screening compound: 1-[6-(3-chlorobenzenesulfonyl)-4-(3,4-difluorophenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine
V021-0227 Screening compound: 1-[6-(3-chlorobenzenesulfonyl)-4-(3,4-difluorophenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-0227
1-[6-(3-chlorobenzenesulfonyl)-4-(3,4-difluorophenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-0227

Molecular Formula

C24H23ClF2N4O3S (C24 H23 ClF2 N4 O3 S)

Compound Name

1-[6-(3-chlorobenzenesulfonyl)-4-(3,4-difluorophenoxy)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl]piperidine

IUPAC name

1-[6-(3-chlorobenzenesulfonyl)-4-(34-difluorophenoxy)-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl]piperidine

SMILES

O=S(c1cccc(Cl)c1)(N(CCc1nc(N2CCCCC2)n2)Cc1c2Oc(cc1)cc(F)c1F)=O

InChI

InChI=1S/C24H23ClF2N4O3S/c25-16-5-4-6-18(13-16)35(32,33)31-12-9-22-19(15-31)23(34-17-7-8-20(26)21(27)14-17)29-24(28-22)30-10-2-1-3-11-30/h4-8,13-14H,1-3,9-12,15H2

InChI Key

GRKYQYBRQCLTLL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19933208

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

520.99

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.156

Distribution Coefficient, logD

6.156

Water Solubility, LogSw

-6.32

Polar Surface Area

61.568

Acid Dissociation Constant (pKa)

20.43

Base Dissociation Constant (pKb)

9.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

V021-0227 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with V021-0227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-0227?
Check Price and Availability of V021-0227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V021-0227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-0227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-0227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-0227 available by request