V021-0303 Screening compound: N-({[1,1'-biphenyl]-4-yl}methyl)-1-{2',6'-dimethoxy-[1,1'-biphenyl]-4-yl}-1H-imidazole-5-carboxamide

V021-0303 Screening compound: N-({[1,1'-biphenyl]-4-yl}methyl)-1-{2',6'-dimethoxy-[1,1'-biphenyl]-4-yl}-1H-imidazole-5-carboxamide
V021-0303 Screening compound: N-({[1,1'-biphenyl]-4-yl}methyl)-1-{2',6'-dimethoxy-[1,1'-biphenyl]-4-yl}-1H-imidazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-0303
N-({[1,1'-biphenyl]-4-yl}methyl)-1-{2',6'-dimethoxy-[1,1'-biphenyl]-4-yl}-1H-imidazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-0303

Molecular Formula

C31H27N3O3 (C31 H27 N3 O3)

Compound Name

N-({[1,1'-biphenyl]-4-yl}methyl)-1-{2',6'-dimethoxy-[1,1'-biphenyl]-4-yl}-1H-imidazole-5-carboxamide

IUPAC name

N-({[11'-biphenyl]-4-yl}methyl)-1-{2'6'-dimethoxy-[11'-biphenyl]-4-yl}-1H-imidazole-5-carboxamide

SMILES

COc1cccc(OC)c1-c(cc1)ccc1-n1c(C(NCc(cc2)ccc2-c2ccccc2)=O)cnc1

InChI

InChI=1S/C31H27N3O3/c1-36-28-9-6-10-29(37-2)30(28)25-15-17-26(18-16-25)34-21-32-20-27(34)31(35)33-19-22-11-13-24(14-12-22)23-7-4-3-5-8-23/h3-18,20-21H,19H2,1-2H3,(H,33,35)

InChI Key

MJLMKEOBRZLCNQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19965527

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

489.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.437

Distribution Coefficient, logD

5.435

Water Solubility, LogSw

-5.53

Polar Surface Area

50.247

Acid Dissociation Constant (pKa)

13.18

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.70

V021-0303 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with V021-0303 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-0303?
Check Price and Availability of V021-0303, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V021-0303 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-0303
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-0303
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-0303 available by request