V021-1356 Screening compound: 2-methyl-4-(3-phenoxyphenyl)-6-{4-[2-(piperidin-1-yl)ethyl]piperazin-1-yl}-2H-pyrazolo[3,4-d]pyrimidin-3-amine

V021-1356 Screening compound: 2-methyl-4-(3-phenoxyphenyl)-6-{4-[2-(piperidin-1-yl)ethyl]piperazin-1-yl}-2H-pyrazolo[3,4-d]pyrimidin-3-amine
V021-1356 Screening compound: 2-methyl-4-(3-phenoxyphenyl)-6-{4-[2-(piperidin-1-yl)ethyl]piperazin-1-yl}-2H-pyrazolo[3,4-d]pyrimidin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-1356
2-methyl-4-(3-phenoxyphenyl)-6-{4-[2-(piperidin-1-yl)ethyl]piperazin-1-yl}-2H-pyrazolo[3,4-d]pyrimidin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-1356

Molecular Formula

C29H36N8O (C29 H36 N8 O)

Compound Name

2-methyl-4-(3-phenoxyphenyl)-6-{4-[2-(piperidin-1-yl)ethyl]piperazin-1-yl}-2H-pyrazolo[3,4-d]pyrimidin-3-amine

IUPAC name

2-methyl-4-(3-phenoxyphenyl)-6-{4-[2-(piperidin-1-yl)ethyl]piperazin-1-yl}-2H-pyrazolo[34-d]pyrimidin-3-amine

SMILES

Cn(c(N)c12)nc2nc(N2CCN(CCN3CCCCC3)CC2)nc1-c1cccc(Oc2ccccc2)c1

InChI

InChI=1S/C29H36N8O/c1-34-27(30)25-26(22-9-8-12-24(21-22)38-23-10-4-2-5-11-23)31-29(32-28(25)33-34)37-19-17-36(18-20-37)16-15-35-13-6-3-7-14-35/h2,4-5,8-12,21H,3,6-7,13-20,30H2,1H3

InChI Key

DNGSLEAVHLJVMJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14250134

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

512.66

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.311

Distribution Coefficient, logD

3.246

Water Solubility, LogSw

-4.62

Polar Surface Area

70.492

Acid Dissociation Constant (pKa)

20.14

Base Dissociation Constant (pKb)

8.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.40

V021-1356 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V021-1356 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-1356?
Check Price and Availability of V021-1356, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V021-1356 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-1356
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-1356
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-1356 available by request