V021-1410 Screening compound: N-(3-chlorophenyl)-4-(2,4-difluorophenoxy)-2-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

V021-1410 Screening compound: N-(3-chlorophenyl)-4-(2,4-difluorophenoxy)-2-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide
V021-1410 Screening compound: N-(3-chlorophenyl)-4-(2,4-difluorophenoxy)-2-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-1410
N-(3-chlorophenyl)-4-(2,4-difluorophenoxy)-2-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-1410

Molecular Formula

C25H25ClF2N6O2 (C25 H25 ClF2 N6 O2)

Compound Name

N-(3-chlorophenyl)-4-(2,4-difluorophenoxy)-2-(4-methylpiperazin-1-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-6-carboxamide

IUPAC name

N-(3-chlorophenyl)-4-(24-difluorophenoxy)-2-(4-methylpiperazin-1-yl)-5H6H7H8H-pyrido[43-d]pyrimidine-6-carboxamide

SMILES

CN(CC1)CCN1c1nc(Oc(ccc(F)c2)c2F)c(CN(CC2)C(Nc3cccc(Cl)c3)=O)c2n1

InChI

InChI=1S/C25H25ClF2N6O2/c1-32-9-11-33(12-10-32)24-30-21-7-8-34(25(35)29-18-4-2-3-16(26)13-18)15-19(21)23(31-24)36-22-6-5-17(27)14-20(22)28/h2-6,13-14H,7-12,15H2,1H3,(H,29,35)

InChI Key

LJDAKKBURISTJC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19933457

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

514.96

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.878

Distribution Coefficient, logD

4.306

Water Solubility, LogSw

-4.93

Polar Surface Area

58.889

Acid Dissociation Constant (pKa)

12.35

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

V021-1410 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with V021-1410 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-1410?
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What is the minimum amount of V021-1410 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-1410
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-1410
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-1410 available by request