V021-1918 Screening compound: 5-chloro-1-[(4-methylphenyl)methyl]-3'-(thiophene-2-carbonyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

V021-1918 Screening compound: 5-chloro-1-[(4-methylphenyl)methyl]-3'-(thiophene-2-carbonyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one
V021-1918 Screening compound: 5-chloro-1-[(4-methylphenyl)methyl]-3'-(thiophene-2-carbonyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-1918
5-chloro-1-[(4-methylphenyl)methyl]-3'-(thiophene-2-carbonyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-1918

Molecular Formula

C23H19ClN2O2S2 (C23 H19 ClN2 O2 S2)

Compound Name

5-chloro-1-[(4-methylphenyl)methyl]-3'-(thiophene-2-carbonyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

IUPAC name

5-chloro-1-[(4-methylphenyl)methyl]-3'-(thiophene-2-carbonyl)-12-dihydrospiro[indole-32'-[13]thiazolidin]-2-one

SMILES

Cc1ccc(CN(C(C23SCCN2C(c2cccs2)=O)=O)c(cc2)c3cc2Cl)cc1

InChI

InChI=1S/C23H19ClN2O2S2/c1-15-4-6-16(7-5-15)14-25-19-9-8-17(24)13-18(19)23(22(25)28)26(10-12-30-23)21(27)20-3-2-11-29-20/h2-9,11,13H,10,12,14H2,1H3/t23-/m0/s1

InChI Key

SSKDLXCJVONPIT-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD19872030

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.581

Distribution Coefficient, logD

5.581

Water Solubility, LogSw

-5.78

Polar Surface Area

32.598

Acid Dissociation Constant (pKa)

27.15

Base Dissociation Constant (pKb)

-3.42

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.70

V021-1918 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V021-1918 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-1918?
Check Price and Availability of V021-1918, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V021-1918 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-1918
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-1918
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-1918 available by request