V021-3267 Screening compound: 1-[(2-chlorophenyl)methyl]-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

V021-3267 Screening compound: 1-[(2-chlorophenyl)methyl]-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one
V021-3267 Screening compound: 1-[(2-chlorophenyl)methyl]-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-3267
1-[(2-chlorophenyl)methyl]-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-3267

Molecular Formula

C25H21ClN2O3S (C25 H21 ClN2 O3 S)

Compound Name

1-[(2-chlorophenyl)methyl]-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

IUPAC name

1-[(2-chlorophenyl)methyl]-3'-(4-methoxybenzoyl)-12-dihydrospiro[indole-32'-[13]thiazolidin]-2-one

SMILES

COc(cc1)ccc1C(N1C(c(cccc2)c2N2Cc(cccc3)c3Cl)(C2=O)SCC1)=O

InChI

InChI=1S/C25H21ClN2O3S/c1-31-19-12-10-17(11-13-19)23(29)28-14-15-32-25(28)20-7-3-5-9-22(20)27(24(25)30)16-18-6-2-4-8-21(18)26/h2-13H,14-16H2,1H3/t25-/m0/s1

InChI Key

CBMBYCOVOCQZHS-VWLOTQADSA-N

MDL Number (MFCD)

MFCD19870582

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.97

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.877

Distribution Coefficient, logD

4.877

Water Solubility, LogSw

-4.89

Polar Surface Area

39.123

Acid Dissociation Constant (pKa)

27.35

Base Dissociation Constant (pKb)

-3.39

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

V021-3267 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V021-3267 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-3267?
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What is the minimum amount of V021-3267 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-3267
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-3267
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-3267 available by request