V021-3304 Screening compound: 3-{[3'-(2-fluorobenzoyl)-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]methyl}benzonitrile

V021-3304 Screening compound: 3-{[3'-(2-fluorobenzoyl)-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]methyl}benzonitrile
V021-3304 Screening compound: 3-{[3'-(2-fluorobenzoyl)-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]methyl}benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-3304
3-{[3'-(2-fluorobenzoyl)-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]methyl}benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-3304

Molecular Formula

C26H20FN3O2S (C26 H20 FN3 O2 S)

Compound Name

3-{[3'-(2-fluorobenzoyl)-5-methyl-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-1-yl]methyl}benzonitrile

IUPAC name

3-{[3'-(2-fluorobenzoyl)-5-methyl-2-oxo-12-dihydrospiro[indole-32'-[13]thiazolidin]-1-yl]methyl}benzonitrile

SMILES

Cc(cc1)cc(C23SCCN2C(c(cccc2)c2F)=O)c1N(Cc1cc(C#N)ccc1)C3=O

InChI

InChI=1S/C26H20FN3O2S/c1-17-9-10-23-21(13-17)26(25(32)29(23)16-19-6-4-5-18(14-19)15-28)30(11-12-33-26)24(31)20-7-2-3-8-22(20)27/h2-10,13-14H,11-12,16H2,1H3/t26-/m0/s1

InChI Key

ONVUGVPWHFZSBV-SANMLTNESA-N

MDL Number (MFCD)

MFCD19872368

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.643

Distribution Coefficient, logD

4.643

Water Solubility, LogSw

-4.50

Polar Surface Area

48.636

Acid Dissociation Constant (pKa)

27.35

Base Dissociation Constant (pKb)

-3.93

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.20

V021-3304 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral HBV Library (10007 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V021-3304 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-3304?
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What is the minimum amount of V021-3304 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-3304
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-3304
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-3304 available by request