V021-4954 Screening compound: 1-(2-methoxyethyl)-4-[6-methyl-2-(1-{[3-(trifluoromethyl)phenyl]methyl}piperidin-4-yl)pyridine-3-carbonyl]piperazine

V021-4954 Screening compound: 1-(2-methoxyethyl)-4-[6-methyl-2-(1-{[3-(trifluoromethyl)phenyl]methyl}piperidin-4-yl)pyridine-3-carbonyl]piperazine
V021-4954 Screening compound: 1-(2-methoxyethyl)-4-[6-methyl-2-(1-{[3-(trifluoromethyl)phenyl]methyl}piperidin-4-yl)pyridine-3-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound V021-4954
1-(2-methoxyethyl)-4-[6-methyl-2-(1-{[3-(trifluoromethyl)phenyl]methyl}piperidin-4-yl)pyridine-3-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V021-4954

Molecular Formula

C27H35F3N4O2 (C27 H35 F3 N4 O2)

Compound Name

1-(2-methoxyethyl)-4-[6-methyl-2-(1-{[3-(trifluoromethyl)phenyl]methyl}piperidin-4-yl)pyridine-3-carbonyl]piperazine

IUPAC name

1-(2-methoxyethyl)-4-[6-methyl-2-(1-{[3-(trifluoromethyl)phenyl]methyl}piperidin-4-yl)pyridine-3-carbonyl]piperazine

SMILES

Cc1ccc(C(N2CCN(CCOC)CC2)=O)c(C2CCN(Cc3cccc(C(F)(F)F)c3)CC2)n1

InChI

InChI=1S/C27H35F3N4O2/c1-20-6-7-24(26(35)34-14-12-32(13-15-34)16-17-36-2)25(31-20)22-8-10-33(11-9-22)19-21-4-3-5-23(18-21)27(28,29)30/h3-7,18,22H,8-17,19H2,1-2H3

InChI Key

RMFWNKMFBUQZHI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19928516

Chemical and Physical Properties

Saltdata

not_available

Molecular Weight

504.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.820

Distribution Coefficient, logD

3.493

Water Solubility, LogSw

-3.86

Polar Surface Area

41.673

Acid Dissociation Constant (pKa)

24.81

Base Dissociation Constant (pKb)

7.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

V021-4954 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V021-4954 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V021-4954?
Check Price and Availability of V021-4954, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V021-4954 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V021-4954
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V021-4954
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V021-4954 available by request