V022-1768 Screening compound: N-(3-fluorophenyl)-1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V022-1768 Screening compound: N-(3-fluorophenyl)-1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V022-1768 Screening compound: N-(3-fluorophenyl)-1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-1768
N-(3-fluorophenyl)-1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-1768

Molecular Formula

C24H19F2N3O2S (C24 H19 F2 N3 O2 S)

Compound Name

N-(3-fluorophenyl)-1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

N-(3-fluorophenyl)-1-[(4-fluorophenyl)methyl]-2-oxo-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

O=C(Nc1cc(F)ccc1)N1C(c(cccc2)c2N2Cc(cc3)ccc3F)(C2=O)SCC1

InChI

InChI=1S/C24H19F2N3O2S/c25-17-10-8-16(9-11-17)15-28-21-7-2-1-6-20(21)24(22(28)30)29(12-13-32-24)23(31)27-19-5-3-4-18(26)14-19/h1-11,14H,12-13,15H2,(H,27,31)/t24-/m0/s1

InChI Key

BCVBQKBPPVRBQK-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD19870094

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.976

Distribution Coefficient, logD

4.976

Water Solubility, LogSw

-4.73

Polar Surface Area

40.400

Acid Dissociation Constant (pKa)

12.63

Base Dissociation Constant (pKb)

-1.75

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

V022-1768 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V022-1768 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-1768?
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What is the minimum amount of V022-1768 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-1768
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-1768
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-1768 available by request