V022-2548 Screening compound: N-(3,4-dimethylphenyl)-5-methoxy-2-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V022-2548 Screening compound: N-(3,4-dimethylphenyl)-5-methoxy-2-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V022-2548 Screening compound: N-(3,4-dimethylphenyl)-5-methoxy-2-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-2548
N-(3,4-dimethylphenyl)-5-methoxy-2-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-2548

Molecular Formula

C28H26F3N3O3S (C28 H26 F3 N3 O3 S)

Compound Name

N-(3,4-dimethylphenyl)-5-methoxy-2-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

N-(34-dimethylphenyl)-5-methoxy-2-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

Cc(cc1)c(C)cc1NC(N1C(c(cc(cc2)OC)c2N2Cc3ccc(C(F)(F)F)cc3)(C2=O)SCC1)=O

InChI

InChI=1S/C28H26F3N3O3S/c1-17-4-9-21(14-18(17)2)32-26(36)34-12-13-38-27(34)23-15-22(37-3)10-11-24(23)33(25(27)35)16-19-5-7-20(8-6-19)28(29,30)31/h4-11,14-15H,12-13,16H2,1-3H3,(H,32,36)/t27-/m0/s1

InChI Key

RDXWLVLZIIIWAK-MHZLTWQESA-N

MDL Number (MFCD)

MFCD19871558

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

541.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.838

Distribution Coefficient, logD

6.838

Water Solubility, LogSw

-5.60

Polar Surface Area

47.944

Acid Dissociation Constant (pKa)

14.57

Base Dissociation Constant (pKb)

-0.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.60

V022-2548 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with V022-2548 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-2548?
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What is the minimum amount of V022-2548 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-2548
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-2548
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-2548 available by request