V022-3335 Screening compound: 1-[(2-chlorophenyl)methyl]-5-methoxy-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

V022-3335 Screening compound: 1-[(2-chlorophenyl)methyl]-5-methoxy-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one
V022-3335 Screening compound: 1-[(2-chlorophenyl)methyl]-5-methoxy-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-3335
1-[(2-chlorophenyl)methyl]-5-methoxy-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-3335

Molecular Formula

C26H23ClN2O4S (C26 H23 ClN2 O4 S)

Compound Name

1-[(2-chlorophenyl)methyl]-5-methoxy-3'-(4-methoxybenzoyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-2-one

IUPAC name

1-[(2-chlorophenyl)methyl]-5-methoxy-3'-(4-methoxybenzoyl)-12-dihydrospiro[indole-32'-[13]thiazolidin]-2-one

SMILES

COc(cc1)ccc1C(N1C(c(cc(cc2)OC)c2N2Cc(cccc3)c3Cl)(C2=O)SCC1)=O

InChI

InChI=1S/C26H23ClN2O4S/c1-32-19-9-7-17(8-10-19)24(30)29-13-14-34-26(29)21-15-20(33-2)11-12-23(21)28(25(26)31)16-18-5-3-4-6-22(18)27/h3-12,15H,13-14,16H2,1-2H3/t26-/m0/s1

InChI Key

XQJIVCVZERCBMP-SANMLTNESA-N

MDL Number (MFCD)

MFCD19872194

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.062

Distribution Coefficient, logD

5.062

Water Solubility, LogSw

-5.19

Polar Surface Area

46.667

Acid Dissociation Constant (pKa)

27.35

Base Dissociation Constant (pKb)

-2.81

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.10

V022-3335 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V022-3335 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-3335?
Check Price and Availability of V022-3335, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V022-3335 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-3335
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-3335
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-3335 available by request