V022-9425 Screening compound: 4-{[5-(2,3-dimethylphenoxy)-2-(4-methoxyphenyl)-3-oxo-2,3-dihydropyridazin-4-yl]amino}-N-[(3-fluorophenyl)methyl]benzamide

V022-9425 Screening compound: 4-{[5-(2,3-dimethylphenoxy)-2-(4-methoxyphenyl)-3-oxo-2,3-dihydropyridazin-4-yl]amino}-N-[(3-fluorophenyl)methyl]benzamide
V022-9425 Screening compound: 4-{[5-(2,3-dimethylphenoxy)-2-(4-methoxyphenyl)-3-oxo-2,3-dihydropyridazin-4-yl]amino}-N-[(3-fluorophenyl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-9425
4-{[5-(2,3-dimethylphenoxy)-2-(4-methoxyphenyl)-3-oxo-2,3-dihydropyridazin-4-yl]amino}-N-[(3-fluorophenyl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-9425

Molecular Formula

C33H29FN4O4 (C33 H29 FN4 O4)

Compound Name

4-{[5-(2,3-dimethylphenoxy)-2-(4-methoxyphenyl)-3-oxo-2,3-dihydropyridazin-4-yl]amino}-N-[(3-fluorophenyl)methyl]benzamide

IUPAC name

4-{[5-(23-dimethylphenoxy)-2-(4-methoxyphenyl)-3-oxo-23-dihydropyridazin-4-yl]amino}-N-[(3-fluorophenyl)methyl]benzamide

SMILES

Cc1cccc(OC(C=NN(c(cc2)ccc2OC)C2=O)=C2Nc(cc2)ccc2C(NCc2cccc(F)c2)=O)c1C

InChI

InChI=1S/C33H29FN4O4/c1-21-6-4-9-29(22(21)2)42-30-20-36-38(27-14-16-28(41-3)17-15-27)33(40)31(30)37-26-12-10-24(11-13-26)32(39)35-19-23-7-5-8-25(34)18-23/h4-18,20,37H,19H2,1-3H3,(H,35,39)

InChI Key

JMOJYCASFMASDJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19840136

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

564.62

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.862

Distribution Coefficient, logD

5.836

Water Solubility, LogSw

-5.53

Polar Surface Area

75.360

Acid Dissociation Constant (pKa)

10.09

Base Dissociation Constant (pKb)

6.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.10

V022-9425 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with V022-9425 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-9425?
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What is the minimum amount of V022-9425 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-9425
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-9425
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-9425 available by request