V022-9877 Screening compound: 1-[(3-fluorophenyl)methyl]-2-oxo-N-[4-(propan-2-yl)phenyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V022-9877 Screening compound: 1-[(3-fluorophenyl)methyl]-2-oxo-N-[4-(propan-2-yl)phenyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V022-9877 Screening compound: 1-[(3-fluorophenyl)methyl]-2-oxo-N-[4-(propan-2-yl)phenyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-9877
1-[(3-fluorophenyl)methyl]-2-oxo-N-[4-(propan-2-yl)phenyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-9877

Molecular Formula

C27H26FN3O2S (C27 H26 FN3 O2 S)

Compound Name

1-[(3-fluorophenyl)methyl]-2-oxo-N-[4-(propan-2-yl)phenyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

1-[(3-fluorophenyl)methyl]-2-oxo-N-[4-(propan-2-yl)phenyl]-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

CC(C)c(cc1)ccc1NC(N1C(c(cccc2)c2N2Cc3cc(F)ccc3)(C2=O)SCC1)=O

InChI

InChI=1S/C27H26FN3O2S/c1-18(2)20-10-12-22(13-11-20)29-26(33)31-14-15-34-27(31)23-8-3-4-9-24(23)30(25(27)32)17-19-6-5-7-21(28)16-19/h3-13,16,18H,14-15,17H2,1-2H3,(H,29,33)/t27-/m0/s1

InChI Key

RRLCCPFAKXQQLY-MHZLTWQESA-N

MDL Number (MFCD)

MFCD19871422

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.254

Distribution Coefficient, logD

6.254

Water Solubility, LogSw

-5.49

Polar Surface Area

40.400

Acid Dissociation Constant (pKa)

14.39

Base Dissociation Constant (pKb)

-1.40

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.90

V022-9877 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V022-9877 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-9877?
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What is the minimum amount of V022-9877 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-9877
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-9877
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-9877 available by request