V022-9878 Screening compound: 1-[(3,4-difluorophenyl)methyl]-N-(4-methoxyphenyl)-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V022-9878 Screening compound: 1-[(3,4-difluorophenyl)methyl]-N-(4-methoxyphenyl)-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V022-9878 Screening compound: 1-[(3,4-difluorophenyl)methyl]-N-(4-methoxyphenyl)-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V022-9878
1-[(3,4-difluorophenyl)methyl]-N-(4-methoxyphenyl)-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V022-9878

Molecular Formula

C25H21F2N3O3S (C25 H21 F2 N3 O3 S)

Compound Name

1-[(3,4-difluorophenyl)methyl]-N-(4-methoxyphenyl)-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

1-[(34-difluorophenyl)methyl]-N-(4-methoxyphenyl)-2-oxo-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

COc(cc1)ccc1NC(N1C(c(cccc2)c2N2Cc(cc3)cc(F)c3F)(C2=O)SCC1)=O

InChI

InChI=1S/C25H21F2N3O3S/c1-33-18-9-7-17(8-10-18)28-24(32)30-12-13-34-25(30)19-4-2-3-5-22(19)29(23(25)31)15-16-6-11-20(26)21(27)14-16/h2-11,14H,12-13,15H2,1H3,(H,28,32)/t25-/m0/s1

InChI Key

QEILAUULHVSWNE-VWLOTQADSA-N

MDL Number (MFCD)

MFCD19871692

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.001

Distribution Coefficient, logD

5.001

Water Solubility, LogSw

-4.54

Polar Surface Area

47.944

Acid Dissociation Constant (pKa)

14.19

Base Dissociation Constant (pKb)

-0.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

V022-9878 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V022-9878 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V022-9878?
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What is the minimum amount of V022-9878 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V022-9878
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V022-9878
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V022-9878 available by request