V023-0555 Screening compound: 1-ethyl-5-fluoro-N-(4-fluorophenyl)-5',5'-dimethyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

V023-0555 Screening compound: 1-ethyl-5-fluoro-N-(4-fluorophenyl)-5',5'-dimethyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide
V023-0555 Screening compound: 1-ethyl-5-fluoro-N-(4-fluorophenyl)-5',5'-dimethyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V023-0555
1-ethyl-5-fluoro-N-(4-fluorophenyl)-5',5'-dimethyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V023-0555

Molecular Formula

C21H21F2N3O2S (C21 H21 F2 N3 O2 S)

Compound Name

1-ethyl-5-fluoro-N-(4-fluorophenyl)-5',5'-dimethyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3]thiazolidine]-3'-carboxamide

IUPAC name

1-ethyl-5-fluoro-N-(4-fluorophenyl)-5'5'-dimethyl-2-oxo-12-dihydrospiro[indole-32'-[13]thiazolidine]-3'-carboxamide

SMILES

CCN(C(C12SC(C)(C)CN1C(Nc(cc1)ccc1F)=O)=O)c(cc1)c2cc1F

InChI

InChI=1S/C21H21F2N3O2S/c1-4-25-17-10-7-14(23)11-16(17)21(18(25)27)26(12-20(2,3)29-21)19(28)24-15-8-5-13(22)6-9-15/h5-11H,4,12H2,1-3H3,(H,24,28)/t21-/m0/s1

InChI Key

MGNDNHXSESWJDB-NRFANRHFSA-N

MDL Number (MFCD)

MFCD19870085

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.950

Distribution Coefficient, logD

4.950

Water Solubility, LogSw

-4.60

Polar Surface Area

40.330

Acid Dissociation Constant (pKa)

12.71

Base Dissociation Constant (pKb)

-0.47

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.33

V023-0555 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with V023-0555 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V023-0555?
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What is the minimum amount of V023-0555 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V023-0555
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V023-0555
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V023-0555 available by request