V023-4244 Screening compound: N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide

V023-4244 Screening compound: N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide
V023-4244 Screening compound: N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound V023-4244
N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

V023-4244

Molecular Formula

C21H21FN2O2S (C21 H21 FN2 O2 S)

Compound Name

N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-1,3-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide

IUPAC name

N-{4-[3-(3-fluoro-4-methylphenyl)-4-oxo-13-thiazolidin-2-yl]phenyl}cyclobutanecarboxamide

SMILES

Cc(ccc(N(C(c(cc1)ccc1NC(C1CCC1)=O)SC1)C1=O)c1)c1F

InChI

InChI=1S/C21H21FN2O2S/c1-13-5-10-17(11-18(13)22)24-19(25)12-27-21(24)15-6-8-16(9-7-15)23-20(26)14-3-2-4-14/h5-11,14,21H,2-4,12H2,1H3,(H,23,26)/t21-/m0/s1

InChI Key

HZLUPXPELUNILM-NRFANRHFSA-N

MDL Number (MFCD)

MFCD19861695

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.397

Distribution Coefficient, logD

3.397

Water Solubility, LogSw

-3.73

Polar Surface Area

39.747

Acid Dissociation Constant (pKa)

12.15

Base Dissociation Constant (pKb)

1.33

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

V023-4244 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with V023-4244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound V023-4244?
Check Price and Availability of V023-4244, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of V023-4244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for V023-4244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for V023-4244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of V023-4244 available by request